
Professor Heneghan cited a trial in JAMA which suggests there are benefits in preventing advanced colorectal adenomas with vitamin D3 supplementation, whereas other trials indicate it does not reduce the risk.
The professor cited a 2016 systematic review, including four trials, which reported a modest “chemopreventive effect” of calcium supplements against recurrent colorectal adenomas.
Adding to the confusion is a Cochrane review on Vitamin D supplementation for prevention of cancer in adults.
“This review concludes there is no firm evidence that vitamin D supplementation decreases or increases cancer occurrence in predominantly elderly community-dwelling women,” reported Professor Heneghan.
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